My current favorite comic strip is
Pearls Before Swine
Other current ones I'll read include Brewster Rockit Space Guy, Rose Is Rose, Dilbert, Sherman's Lagoon, etc.
Rose Is Rose was my favorite prior, a good and imaginative family-friendly strip, but seems to have lost something when a new guy took over.
Dilbert was a good popular strip during my cubicle days. It still has its moments.
I liked the 80s era of strips. Bloom County was my favorite during my college days. The Far Side and Calvin & Hobbes were great.